Anti-PSD95 MAGUK Scaffold Protein Mouse Monoclonal Antibody
| Cat Number: | MAB-95054 |
|---|---|
| Conjugate: | unconjugated |
| Size: | 100 μL |
| Clone: | K28/42 |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG2a,κ |
| Immunogen: | Recombinant protein corresponding to Human PSD95 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Applications Dilution WB 1: 500-1: 1000 |
| Molecular: | 95 kDa |
| Purification: | Affinity purification |
| Synonyms: | DLG4, PSD95, SAP-90, SAP90, Dlgh4, PSD-95, SAP90A, discs large homolog 4, discs large MAGUK scaffold protein 4 |
| Background: | Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. |
| Form: | Liquid |
| Buffer: | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
WB analysis of PSD95. Sample: Protein treated by RIPA Lysis Buffer . Blocking buffer: 3% Nonfat dry milk in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG , 1: 3000, RT, 1h.