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APLP-1 rabbit Polyclonal Antibody

Cat Number: ABE3788
Conjugate: unconjugated
Size: 100 ug
Clone: Polyclonal
Concentration: 1 mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from APLP-1 . at AA range: 360-440
Reactivity: Human;Mouse
Applications: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Molecular: 72kD
Purification: The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms: APLP1; Amyloid-like protein 1; APLP; APLP-1
Background:

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Form: liquid
Buffer: Liquid in PBS containing 50% glycerol, 0.5%BSAand0.02% sodium azide.
Storage: Store at -20°C. Avoid repeated freeze-thawcycles
Western Blot analysis of extracts from K562 cells, using APLP-1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Western Blot analysis of extracts from K562 cells, using APLP-1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded mouse-ovary, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-ovary, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-ovary, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-ovary, antibody was diluted at 1:100