Bright Violet 450 Anti-Mouse CD11c Antibody[N418]
| Cat Number: | MAB0991UQ |
|---|---|
| Conjugate: | BrightViolet 450 |
| Size: | 100μg |
| Clone: | Monoclonal |
| Concentration: | 0.5 mg/mL |
| Host: | Armenian Hamster |
| Isotype: | Armenian Hamster IgG |
| Reactivity: | Mouse |
| Applications: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
| Synonyms: | Itgax |
| Background: | CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54. |
| Form: | Liquid |
| Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
C57BL/6 murine splenocytes are stained with FITC Anti-Mouse MHC II Antibody and brightViolet 450 Anti-Mouse CD11c Antibody (Left). Splenocytes are stained with FITC Anti-Mouse MHC II Antibody and Bright Violet 450 Armenian Hamster IgG Isotype Control (Right).