Calnexin/CANX Mouse Monoclonal Antibody
| Cat Number: | MAB-94756 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 200 ug |
| Clone: | 8D10B3 |
| Concentration: | Adding 0.2 ml of distilled water will yield a concentration of 1mg/ml. |
| Host: | Mouse |
| Isotype: | IgG2b |
| Immunogen: | E.coli-derived human Calnexin/CANX recombinant protein. |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blot: 1:1000 Immunohistochemistry(Paraffin-embedded Section): 1:100 Immunocytochemistry: 1:100 Immunofluorescence: 1:100 Flow Cytometry, 1-3 ug/1x106 cells, Human |
| Molecular Weight: | 95 kDa |
| Purification: | Immunogen affinity purified. |
| Background: | Calnexin (CNX) is a 67 kDa integral protein of the endoplasmic reticulum. This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Form: | Lyophilized |
| Buffer: | Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4. |
| Storage: | At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. |