CD133 Mouse Monoclonal Antibody
| Cat Number: | MABN81015 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Immunogen: | Synthesized peptide of human CD133. |
| Reactivity: | Human |
| Applications: | IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular: | 133kDa |
| Purification: | Affinity purification |
| Synonyms: | RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061 |
| Background: | This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Form: | liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Flow cytometric analysis of Hela cells using CD133 mouse mAb (blue) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human breast cancer tissues (left) and human esophageal cancer tissues (right) using CD133 mouse mAb with DAB staining.