CD4 Rabbit Monoclonal Antibody
| Cat Number: | MABN21401 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 0.3mg/ml |
| Host: | Rabbit |
| Isotype: | IgG,Kappa |
| Immunogen: | A synthetic peptide of human CD4 |
| Reactivity: | Human |
| Applications: | WB 1:1000-1:5000;IHC 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000 |
| Molecular: | 55kD |
| Purification: | Protein A |
| Synonyms: | T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD antigen CD4 |
| Background: | Cell localization:Membrane.CD4 molecule(CD4) Homo sapiens This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010] |
| Form: | Liquid |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
| Storage: | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
Western blot analysis of lysates from THP-1 cells, using CD4 Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody was used to detect the antibody.