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CDX2 Mouse Monoclonal antibody

Cat Number: MAB-94764
Conjugate: Unconjugated
Size: 100 ug
Clone: C-11
Concentration: 1mg/ml
Host: Mouse
Isotype: IgG1
Immunogen: Synthetic Peptide
Reactivity: Human; Mouse, Rat
Applications:

WesternBlot:1/1000
Immunohistochemistry:1/200
Molecular Weight: 42kDa
Synonyms: Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2
Background:

CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of
intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to
CK20.
Form: Liquid
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage: Store at -20°C. Avoid repeated freeze-thaw cycles.
MAB-94764-1

Western blot analysis of) 293T 2)Mouse Heart tissue with CDX2 mAb diluted at:2000.

MAB-94764-2

IHC staining of human rectal cancer tissue with CDX2 mouse mAb diluted at:200.