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Connexin 25 Rabbit Polyclonal Antibody

Cat Number: ABN09228
Conjugate: Unconjugated
Size: 100μL
Clone: Polyclonal
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70
Reactivity: Human,Rat,Mouse
Applications: WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular: 24kDa
Purification: Affinity purification
Synonyms: GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25
Background:

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta.,

Form: Liquid
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.