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Cytochrome P450 2A6/7/13 Rabbit Polyclonal Antibody

Cat Number: ABN00602
Conjugate: Unconjugated
Size: 100μL
Clone: Polyclonal
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the Internal region of human CYP2A6/7/13.
Reactivity: Human
Applications: WB 1:500-1:1000,ELISA 1:5000-1:20000
Molecular: Calculated MW: 56 kDa; Observed MW: 56 kDa
Purification: Affinity Purification
Synonyms: CYP2A6; CYP2A3; Cytochrome P450 2A6; 1; 4-cineole 2-exo-monooxygenase; CYPIIA6; Coumarin 7-hydroxylase; Cytochrome P450 IIA3; Cytochrome P450(I); CYP2A7; Cytochrome P450 2A7; CYPIIA7; Cytochrome P450 IIA4; CYP2A13; Cytochrome P450 2A13; CYPIIA13
Background:

Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Form: Liquid
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.