DBF4 Rabbit Monoclonal Antibody
| Cat Number: | MABN84580 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human DBF4 |
| Reactivity: | Human |
| Applications: | WB 1:1000-1:2000 |
| Molecular: | Calculated MW: 77 kDa ; Observed MW: 80 kDa |
| Purification: | Affinity Purification |
| Synonyms: | ASK; CHIF; DBF4; DBF4 zinc finger A; DBF4A; ZDBF1;;DBF4 |
| Background: | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at ‘Ser-40’ and ‘Ser-53’ and then is involved in regulating the initiation of DNA replication during cell cycle. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |