DOK1 Rabbit Monoclonal Antibody
| Cat Number: | MABN84610 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human DOK1 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:2000,ICC 1:50-1:200 |
| Molecular: | Calculated MW: 52 kDa ; Observed MW: 65 kDa |
| Purification: | Affinity Purification |
| Synonyms: | DOK1; p62(dok); P62DOK; pp62;;DOK1 |
| Background: | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |