EP4 Rabbit Polyclonal Antibody
| Cat Number: | AB-J7155 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PE2R4. AA range:321-370 |
| Reactivity: | Human;Rat;Mouse; |
| Applications: | Western Blot: 1/500 – 1/2000 |
| Molecular Weight: | 55kDa |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Synonyms: | PTGER4; PTGER2; Prostaglandin E2 receptor EP4 subtype; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostanoid EP4 receptor |
| Background: | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage: | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Western Blot analysis of various cells using EP4 Polyclonal Antibody
Western Blot analysis of COLO205 cells using EP4 Polyclonal Antibody
Western blot analysis of lysates from COLO205 cells, using PE2R4 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of MCF7 cells, using PE2R4 Antibody. The picture on the right is blocked with the synthesized peptide.