FAM111B Rabbit Polyclonal Antibody
| Cat Number: | ABN10809 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330 |
| Reactivity: | Human,Rat,Mouse |
| Applications: | IHC 1:100-1:200,ICC/IF 1:50-1:200,ELISA 1:5000-1:10000 |
| Purification: | Affinity purification |
| Synonyms: | FAM111B; CANP; Protein FAM111B; Cancer-associated nucleoprotein |
| Background: | This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin-like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014],sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the FAM111 family., |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |