FE65 Rabbit Monoclonal antibody
| Cat Number: | MABN02996 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human FE65 |
| Reactivity: | Human |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 |
| Molecular: | 100 kDa |
| Purification: | Affinity purification |
| Synonyms: | APBB1; Protein Fe65; RIR |
| Background: | Transcription coregulator that can have both coactivator and corepressor functions. Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain. Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. |
| Form: | liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Immunocytochemistry analysis of FE65 (green) in 293T using FE65 antibody, and DAPI (blue).
Western blot analysis of FE65 in A549, U251 lysates using FE65 antibody.
Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using FE65 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.