GPX1 (13J4) Rabbit Monoclonal Antibody
| Cat Number: | MABN11726 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | 13J4 |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human Glutathione Peroxidase 1 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:5000,IP 1:10-1:100 |
| Molecular: | 22kDa |
| Purification: | Affinity purification |
| Synonyms: | GPX1; GSHPX1; MGC14399; MGC88245; Glutathione Peroxidase 1 |
| Background: | Glutathione peroxidase 1 (GPX1) is a cytosolic selenoprotein which reduces hydrogen peroxide to water. GPX1 is the most abundant and ubiquitous among the five GPX isoforms identified so far. It is an important component in the anti-oxidative defense in cells and is associated with a variety of disease conditions, such as colon cancer, coronary artery disease and insulin resistance. Protects the hemoglobin in erythrocytes from oxidative breakdown. In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism (PubMed:11115402). |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol |
| Storage: | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Western blot analysis of GPX1 expression in SH SY5Y cell lysate.