HFE Mouse Monoclonal Antibody
| Cat Number: | MABN81041 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Immunogen: | Purified recombinant fragment of human HFE expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | ICC 1:200-1:1000,ELISA 1:5000-1:20000 |
| Molecular: | 40kDa |
| Purification: | Affinity Purification |
| Synonyms: | HH; HFE1; HLA-H; MVCD7; TFQTL2; MGC103790; dJ221C16.10.1 |
| Background: | The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. |
| Form: | Liquid |
| Buffer: | Ascitic fluid containing 0.03% sodium azide. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |