HGFA Rabbit Polyclonal Antibody
| Cat Number: | ABN12008 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human HGFA. |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000,ELISA 1:20000-1:40000 |
| Molecular: | 70kDa |
| Purification: | Affinity purification |
| Synonyms: | HGFAC; Hepatocyte growth factor activator; HGF activator; HGFA |
| Background: | This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],caution:It is uncertain whether Met-1 is the initiator.,function:Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 fibronectin type-I domain.,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subcellular location:Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.,subunit:Heterodimer of a short chain and a long chain linked by a disulfide bond.,tissue specificity:Liver., |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |