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HISTONE H2A Rabbit Polyclonal Antibody

Cat Number: AB-E8591
Conjugate: unconjated
Size: 100 ug
Clone: Polyclonal
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the Internal region of human Histone H2A. 20-50
Reactivity: Human, Mouse, Rat
Applications: Western Blot 1:500- 1:2000 IHC(p) 1:100-1:300 Elisa: 1:20000  
Molecular Weight: 15kd
Purification: affinity purified
Synonyms: HIST1H2AG; H2AFP; HIST1H2AI; H2AFC; HIST1H2AK; H2AFD; HIST1H2AL; H2AFI; HIST1H2AM; H2AFN; Histone H2A type 1; H2A.1; Histone H2A/p
Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones  (H2A, H2B, H3, and H4) form an octamer, around which ,approximately 146 bp of DNA is wrapped in repeating units,called nucleosomes. The linker histone, H1, interacts with  linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family.
Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.

Form: Liquid
Buffer: PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Storage: Store at -20°C. Avoid repeated freeze-thaw cycles.