Huntingtin Protein
| Cat Number: | MAB-94354 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ul |
| Clone: | EM48 |
| Concentration: | 1mg/ml |
| Host: | Ms |
| Isotype: | IgG1 |
| Immunogen: | GST fusion protein from the first 256 amino acids from human huntingtin with the deletion of the polyglutamine tract. |
| Reactivity: | Hu |
| Applications: | * ELISA |
| Purification: | Ascites |
| Background: | Reacts with human huntingtin protein (both native and recombinant protein). MAB94354 reacts with mutant huntingtin in patients and in transgenic animals that express different numbers of repeats. Thus, it should recognize different forms of mutant huntingtin |
| Form: | Liquid |
| Storage: | Store at -20°C (up to 3 years) Avoid repeat freezing and thawing cycles. Does not contain any preservative |
IHC on striatum of WT & R6/2 (transgenic mice affected Huntington) using MAB-5374 from Millipore and MAB-94354 from Immunological Sciences , for both antibodies the dilutions are : 1:150
WB on striatum of WT, R6/2 (transgenic mice)
using MAB-94354 at a dilution of: 1:1000
References
Images provide courtesy of: Dr.Vittorio Maglione & Dr. Alba Di Pardo
Centre for Neurogenetics and Rare Diseases
IRCCS Neuromed – Pozzilli-Italy