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IL-17R alpha Rabbit Polyclonal Antibody

Cat Number: AB-E9039
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: The antiserum was produced against synthesized peptide derived from human IL17RA. AA
Reactivity: Human;Mouse
Applications:

Western Blot: 1/500 – 1/2000

ELISA: 1/40000

Molecular Weight: 90kD
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms: IL17RA; IL17R; Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD antigen CD217
Background:

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous  type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors,
this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms

Form: Liquid
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20°C. Avoid repeated freeze-thaw cycles.
AB-E9039-1

Western blot analysis of the lysates from HeLa cells using IL17RA antibody.