Interleukin-6
Cat Number: | MAB-94635 |
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Conjugate: | Unconjugated |
Size: | 100 ug |
Clone: | I621 |
Concentration: | 1mg/ml |
Host: | Rabbit |
Isotype: | IgG |
Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human IL6. AA range:131-180 |
Reactivity: | Hu,Ms, Rt |
Applications: | Western Blot: 1/500 - 1/2000. Immunohistochemistry (paraffin-ebedded tissues): 1:100-300 Immunofluorescence: 1:100-300 ELISA: 1/20000 |
Molecular Weight: | 23kDa |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Synonyms: | IL6; IFNB2; Interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2 |
Background: | This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. |
Form: | Liquid |
Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Storage: | Store at -20℃. Avoid freeze / thaw cycles. |