MGMT Rabbit Monoclonal Antibody
| Cat Number: | MABN85099 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human MGMT |
| Reactivity: | Human |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100 |
| Molecular: | Calculated MW: 22 kDa; Observed MW: 22 kDa |
| Purification: | Affinity Purification |
| Synonyms: | Methylated-DNA--protein-cysteine methyltransferase |
| Background: | MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O(6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents. |
| Form: | Liquid |
| Buffer: | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |