The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator ofsmooth muscle cell differentiation. The encoded protein is predominantly nuclear and may helptransduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocationevent that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocationhas been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.