MOG /Myelin oligodendrocyte glycoprotein
| Cat Number: | MAB-94594 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100ug |
| Clone: | ARC0879 |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Myelin oligodendrocyte glycoprotein |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:500 – 1:1000 |
| Molecular Weight: | 28kDa |
| Purification: | Affinity purification |
| Synonyms: | BTN6; BTNL11; MOGIG2; NRCLP7 |
| Background: | The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of extracts of various cell lines, using Myelin oligodendrocyte glycoprotein
antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL West Pico Plus.
Exposure time: 10s.
Immunofluorescence analysis of rat brain using Myelin oligodendrocyte glycoprotein antibody at dilution of 1:100
(40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of mouse brain using Myelin oligodendrocyte glycoprotein antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.