Neuregulin 1 SMDF Rabbit Polyclonal Antibody
| Cat Number: | AB-81704 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NRG1 isoform-10. AA range:1-50 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 |
| Molecular Weight: | 44kD |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Synonyms: | Pro-neuregulin-1 membrane-bound isoform; Pro-NRG1; NRG1; GGF; HGL; HRGA; NDF; SMDF |
| Background: | The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing.These isoforms are expressed in a tissue-specific manner and differ significantly in their structure,and are classified as types I, II, III, IV, V and VI.Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage: | Store at -20°C. Avoid repeated freeze-thaw cycles. |