Neuron Navigator 1 Rabbit Polyclonal Antibody
| Cat Number: | ABN14614 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Synthesized peptide derived from Neuron Navigator 1 . at AA range: 510-590 |
| Reactivity: | Human,Mouse |
| Applications: | IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:20000-1:40000 |
| Molecular: | 200kDa |
| Purification: | Affinity purification |
| Synonyms: | NAV1; KIAA1151; KIAA1213; POMFIL3; STEERIN1; Neuron navigator 1; Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1 |
| Background: | This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],developmental stage:Expressed in fetal brain and heart.,function:May be involved in neuronal migration.,similarity:Belongs to the Nav/unc-53 family.,subcellular location:Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones.,subunit:Interacts with tubulin.,tissue specificity:Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta., |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |