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NOS1(n/NOS)

Cat Number: AB-84226
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: Recombinant Protein of human NOS1
Reactivity: Hu, Ms, Rt
Applications:

Western Blot: 1:1000
Immunohistochemistry: 1:50-1:200
Immunoprecipitation: 1:20-1:50

Molecular: 160kDa
Purification: Aff. Pur.
Background:

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5′ UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testisspecific) have been found for this gene.

Form: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20°C, and avoid repeat freeze-thaw cycles.
AB-84226-1.jpg

Western blot analysis of extracts of mouse brain cell line, using NOS1 antibody.