Olig2 (15Z2) Rabbit Monoclonal Antibody
| Cat Number: | MABN15345 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | 15Z2 |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:50-1:200 |
| Molecular: | 32kDa |
| Purification: | Affinity purification |
| Synonyms: | Oligo2; bHLHb1; Class E basic helix-loop-helix protein 19; bHLHe19; OLIG2; BHLHB1; BHLHE19; PRKC; |
| Background: | Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. |
| Form: | liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage: | Store at 4°C short term. Aliquot and store at -15098°C long term. Avoid freeze/thaw cycles. |
Western blot analysis of Olig2 in Human oligodendroglioma lysate.