Olig2 Rabbit Monoclonal Antibody
| Cat Number: | MABN87626 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | OL-02 |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:50-1:200 |
| Molecular: | 38 kDa |
| Purification: | Affinity purification |
| Synonyms: | BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19 |
| Background: | This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. |
| Form: | liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Western blot analysis of extracts from Mouse brain tissue using OLIG2 at 1:1000.