PARK7 Mouse Monoclonal Antibody
| Cat Number: | MABN82908 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Immunogen: | Purified recombinant fragment of human PARK7 (AA: 1-189) expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular: | 8kDa |
| Purification: | Affinity purification |
| Synonyms: | DJ1; DJ-1; GATD2; HEL-S-67p |
| Background: | The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. |
| Form: | liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using PARK7 mouse mAb against A549 (1), A431 (2),K562 (3),Hela(4), SH-SY5Y (5) and SW480 (6) cell lysate.
Flow cytometric analysis of HepG2 cells using PARK7 mouse mAb (green) and negative control (red).