PDE4B/C/D Rabbit Polyclonal Antibody
| Cat Number: | ABE3162 |
|---|---|
| Conjugate: | unconjugated |
| Size: | 100 ug |
| Clone: | Polyclonal |
| Concentration: | 1 mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PDE4D. AA range:156-205 |
| Reactivity: | Human;Mouse;Rat |
| Applications: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Molecular: | 76kD |
| Purification: | The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Synonyms: | PDE4B; DPDE4; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43 |
| Background: | This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014], |
| Form: | liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5%BSAand0.02% sodium azide. |
| Storage: | Store at -20°C for 1 year. Avoid repeated freeze-thawcycles. |
Western Blot analysis of various cells using PDE4B/C/D Polyclonal Antibody
Western Blot analysis of K562 cells using PDE4B/C/D Polyclonal Antibody
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using PDE4D Antibody. The picture on the right is blocked with the synthesized peptide.