PE Anti-Human CD80 Antibody[2F4]
| Cat Number: | MAB1365D |
|---|---|
| Conjugate: | PE |
| Size: | 100 ug |
| Clone: | 2F4 |
| Host: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Reactivity: | Human |
| Applications: | FCM Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Molecular: | 60 kD |
| Synonyms: | B7-1;B7;BB1 |
| Background: | CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation. |
| Form: | Liquid |
| Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage: | Keep as concentrated solution. This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |