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Phospho-AMPKα1/2 (T183/172)

Cat Number: ABP-0432
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A phospho specific peptide corresponding to residues surrounding T172 of human AMPKα
Reactivity: Hu, Ms, Rt
Applications:

WB

Molecular: 64kDa
Purification: Affinity purification
Synonyms: AMPKa1/AMPKa2
Background:

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is thecatalytic subunit of the 5′-prime-AMP-activated protein kinase (AMPK). AMPK is a cellularenergy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activatedby the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of anumber of key metabolic enzymes through phosphorylation. It protects cells fromstresses that cause ATP depletion by switching off ATP-consuming biosyntheticpathways. Alternatively spliced transcript variants encoding distinct isoforms have beenobserved. [provided by RefSeq, Jul 2008]

Form: liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles