Phospho-AMPKα1/2 (T183/172)
| Cat Number: | ABP-0432 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding T172 of human AMPKα |
| Reactivity: | Hu, Ms, Rt |
| Applications: | WB |
| Molecular Weight: | 64kDa |
| Purification: | Affinity purification |
| Synonyms: | AMPKa1/AMPKa2 |
| Background: | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is thecatalytic subunit of the 5′-prime-AMP-activated protein kinase (AMPK). AMPK is a cellularenergy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activatedby the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of anumber of key metabolic enzymes through phosphorylation. It protects cells fromstresses that cause ATP depletion by switching off ATP-consuming biosyntheticpathways. Alternatively spliced transcript variants encoding distinct isoforms have beenobserved. [provided by RefSeq, Jul 2008] |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles |