Phospho-C-KIT-Y721
| Cat Number: | ABP-0385 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to phosphorylation site of tyrosine 721 of Human c-Kit |
| Reactivity: | Hu, Ms, Rt |
| Applications: | WB 1:1000 |
| Molecular Weight: | 145 kDa |
| Synonyms: | PBT; SCFR; C-Kit; CD117; |
| Background: | This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of extracts from Hela cells untreated or treated using c-Kit(Phospho-Tyr721) Antibody