Phospho-eNOS-S1177
| Cat Number: | AB-83619 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Reactivity: | Hu, Ms |
| Applications: | WB: 1:500-1:2000 IHC: 1:50-1:200 |
| Molecular Weight: | 133 kDa |
| Purification: | Polyclonal antibodies are produced by immunizing rabbits with a synthetic phospho-peptide (KLH-coupled) corresponding to residues surrounding Ser1177 of human eNOS. Antibodies are purified by protein A and peptide affinity chromatography. |
| Background: | Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Phospho-eNOS (Ser1177) Antibody detects endogenous levels of eNOS only when phosphorylated at Ser1177. |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol,pH7.3 |
| Storage: | Store at -20°C, and avoid repeat freeze-thaw cycles. |