Phospho-HDAC4 (S632)

Cat Number: ABP-0359
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A phospho specific peptide corresponding to residues surrounding S632 of human HDAC4
Reactivity: Hu, Ms, Rt

WB 1:500-1:2000

Molecular Weight: 140kDa
Purification: Affinity purification

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Form: liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20oC or -80oC. Avoid freeze / thaw cycles.

Western blot analysis of extracts from 293 cells using Phospho-HDAC4-S632 antibody