|Immunogen:||A phospho specific peptide corresponding to residues surrounding Ser529 of human NFKB-p65|
|Reactivity:||Hu, Ms, Rt, Monkey|
Western Blotting 1:1000
|Molecular:||"65 kDa "|
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappaB moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, NFKB-P65, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, NFKB-P65. Four transcript variants encoding different isoforms have been found for this gene.
|Buffer:||PBS with 0.02% sodium azide, 50% glycerol, pH7.3, BSA.|
|Storage:||Store at -20° C. Avoid freeze / thaw cycles.|
Western blot analysis of extracts from 293 cells using Phospho-NFKB-p65 (Ser529) antibody.