Phospho-NFκB-p65 (T435)

Cat Number: ABP-0447
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A phospho specific peptide corresponding to residues surrounding Thr435 of human NFKB-p65
Reactivity: Hu, Ms, Rt, Monkey

Western Blotting 1:1000

Molecular: 65 kDa
Purification: Affinity purification
Synonyms: p65; NFKB3; RELA

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa¬B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, NFKB-P65, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, NFKB-P65. Four transcript variants encoding different isoforms have been found for this gene.

Form: liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3, BSA.
Storage: Store at -20° C. Avoid freeze / thaw cycles.

Western blot analysis of extracts from Hela cells, using Phospho-NFKB-p65 (Thr435) antibody.