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Phospho-NFκB-p65 (T505)

Cat Number: ABP10785
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Reactivity: Hu, Ms, Rt
Applications:

IHC-p, ELISA

Molecular: 65 kDa
Purification: Affinity purification
Synonyms: NFKB3; RELA
Background:

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappaB moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, NFKB-P65, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, NFKB-P65. Four transcript variants encoding different isoforms have been found for this gene.

Form: liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3, BSA.