Phospho-NFκB-p65 (T435)
| Cat Number: | ABP-0447 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Thr435 of human NFKB-p65 |
| Reactivity: | Hu, Ms, Rt, Monkey |
| Applications: | Western Blotting 1:1000 |
| Molecular Weight: | 65 kDa |
| Purification: | Affinity purification |
| Synonyms: | p65; NFKB3; RELA |
| Background: | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa¬B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, NFKB-P65, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, NFKB-P65. Four transcript variants encoding different isoforms have been found for this gene. |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3, BSA. |
| Storage: | Store at -20° C. Avoid freeze / thaw cycles. |
Western blot analysis of extracts from Hela cells, using Phospho-NFKB-p65 (Thr435) antibody.