Phospho-RyR-2 (S2815)
| Cat Number: | ABP-0624 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Ser2815 of human RYR2. |
| Reactivity: | Hu |
| Applications: | WB 1:1000 |
| Molecular Weight: | 565kDa |
| Purification: | Affinity purification |
| Synonyms: | Ryanodine receptor 2, ARVC2;ARVD2;RYR-2;RyR;VTSIP |
| Background: | This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles |