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Phospho-Src-Y527

Cat Number: ABP-0470
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A phospho specific peptide corresponding to residues surrounding Y527 of human Src.
Reactivity: Hu
Applications:

WB 1:1000

Molecular: 60kDa
Purification: Affinity purification
Background:

This gene is highly similar to the v-src gene of Rous sarcoma virus. This protooncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Form: liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
ABP-0470-1.jpg

Western blot analysis of extracts of various cell lines, using Phospho-Src-Y527 antibody.