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Phospho-Tau (S396)

Cat Number: ABP-0163
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A phospho specific peptide corresponding to residues surrounding S396 of human MAPT
Reactivity: Hu, Ms, Rt
Applications:

Western Blot: 1:1000 Immunohistochemistry (paraffin embedded tissues) 1:50-1:100

Molecular: 79kDa
Purification: Affinity purification
Synonyms: TAU;MSTD;PPND;DDPAC;MAPTL;MTBT1;MTBT2;FTDP-17
Background:

This gene encodes the microtubμle-associated protein tau (MAPT) whose transcript undergoes complex, regμlated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer’s disease, Pick’s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Form: liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
ABP-0163-1.jpg

Western blot analysis of extracts from mouse brain tissue, using phospho-Tau -S396 antibody.

ABP-0163-2.jpg

Immunohistochemical analysis of paraffin-embedded rat hippocampal region tissue from a model with Alzheimer, using phospho-Tau -S396 antibody.