Phospho-Trk A (S791)
| Cat Number: | ABP-0272 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S791 of human TRKA. |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:1000 Immunofluorescence: 1:100 |
| Molecular Weight: | 140kDa |
| Purification: | Affinity purification |
| Background: | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivityto pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
| Form: | liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles |
Western blot analysis of extracts from Rat and Mouse brain tissue using Phospho-TRKA-Ser791 antibody.
Immunofluorescence staining of methanol-fixed Hela cells using Phospho-TRKA-Ser791 antibody.