Top

Phospho-Trk A (S791)

Cat Number: ABP-0272
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A phospho specific peptide corresponding to residues surrounding S791 of human TRKA.
Reactivity: Hu, Ms, Rt
Applications:

Western Blot: 1:1000 Immunofluorescence: 1:100

Molecular: 140kDa
Purification: Affinity purification
Background:

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivityto pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Form: liquid
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20℃. Avoid freeze / thaw cycles
ABP-0272-1.jpg

Western blot analysis of extracts from Rat and Mouse brain tissue using Phospho-TRKA-Ser791 antibody.

ABP-0272-2.jpg

Immunofluorescence staining of methanol-fixed Hela cells using Phospho-TRKA-Ser791 antibody.