Phospho-YAP1-S127 pAb
| Cat Number: | ABP-0489 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A synthetic phosphorylated peptide around S127 of human YAP1. |
| Reactivity: | Hu, Ms,Rt |
| Applications: | Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:50 - 1:200 Immunofluorescence: 1:50 - 1:100 |
| Molecular Weight: | 68kDa |
| Synonyms: | COB1;YAP;YAP2;YAP65;YKI;YAP1 |
| Background: | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |