PLP1 Rabbit Polyclonal Antibody
| Cat Number: | AB-83554 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-150 of human PLP1. |
| Reactivity: | Human,Mouse,Rat |
| Applications: | Western Blot: 1:1000 - 1:5000 Immunohistochemistry (paraffin-embedded tissues): 1:50 - 1:200 Immunofluorescence: 1:50 - 1:200 Immunocytochemistry: 1:50 - 1:200 ELISA Recommended starting concentration is 1 μg/mL. |
| Molecular Weight: | 20-25kDa |
| Purification: | Affinity purification |
| Synonyms: | PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20; PLP1 |
| Background: | This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction,stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. |
| Form: | Liquid |
| Buffer: | PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |