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SOD1

Cat Number: MAB-94600
Size: 100 ug
Clone: SO-F
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A synthesized peptide derived from human SOD1
Reactivity: Hu, Rt, Ms
Applications:

Western Blot: 1:500 – 1:2000

Molecular: 16kDa
Purification: Aff. Pur.
Synonyms: ALS; ALS1; HEL-S-44; IPOA; SOD; hSod1; homodimer
Background:

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Form: Liquid
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
MAB-94600-1.jpg

Western blot analysis of extracts of various cell lines, using SOD1 Rabbit mAb at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG
(H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL West Pico Plus.
Exposure time: 1s.

MAB-94600-2.jpg

Western blot analysis of extracts of various
cell lines, using SOD1 Rabbit mAb at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit
IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL West Pico Plus.
Exposure time: 10s.

MAB-94600-3.jpg

Review for SOD1 Rabbit mAb
Experiment Type Western blot(WB)

References

References for SOD1 Rabbit mAB
Product:SOD1 Rabbit mAb
Journal:VIRUSES-BASEL
Application:WB
IF:3.464
Species:Homo sapiens
PMID:26761025
Title:The Influenza Virus H5N1 Infection Can Induce ROS Production for Viral Replication and Host Cell Death in A549 Cells Modulated by Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression

References for SOD1 Rabbit mAb
Product:SOD1 Rabbit mAb
Journal:Journal of Surgical Research
Application:WB
IF:2.188
Species:Mus musculus
PMID:29605032
Title:GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice

References for SOD1 Rabbit mAb
Product:SOD1 Rabbit mAb
Journal:Pharmacological research
Application:WB
IF:4.89
Species:Mus musculus
PMID:30986544
Title:LongShengZhi Capsule reduces carrageenan-induced thrombosis by reducing activation of platelets and endothelial cells.

References for SOD1 Rabbit mAb
Product:SOD1 Rabbit mAb
Journal:Molecular carcinogenesis
Application:WB, Co-IP
IF:3.85
Species:Mus musculus
PMID:31066116
Title:MARVELD1 interacting with catalase regulates reactive oxygen species metabolism and mediates the sensitivity to chemotherapeutic drugs in epithelial tumors of the reproductive system.

References for SOD1 Rabbit mAb
Product:SOD1 Rabbit mAb
Journal:Mediators of Inflammation
Application:WB
IF:3.54
Species:Bos taurus
PMID:31011285
Title:The Differential Expression of Mitochondrial Function-Associated Proteins and Antioxidant Enzymes during Bovine Herpesvirus 1 Infection: A Potential Mechanism for Virus Infection-Induced Oxidative Mitochondrial Dysfunction

References for SOD1 Rabbit mAb
Product: SOD1 Rabbit mAb
Journal: Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society
Application:WB:
IF:3.64
Species:Rattus norvegicus
PMID: 32273812
Title: Liraglutide attenuates gefitinib-induced cardiotoxicity and promotes cardioprotection through the regulation of MAPK/NF-κB signaling pathways

References for SOD1 Rabbit mAb
Product:SOD1 Rabbit mAb
Journal:FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Application:WB
IF:5.39
Species:Mus musculus
PMID:31690123
Title:The classic metal-sensing transcription factor MTF1 promotes myogenesis in response to copper
References for SOD1 Rabbit mAb
Product:SOD1 Rabbit mAb
Journal:Drug Design Development and Therapy
Application:WB
IF:3.208
Species:us musculus
PMID:30863013
Title:Maresin 1 mitigates renal ischemia/reperfusion injury in mice via inhibition of the TLR4/MAPK/NF-κB pathways and activation of the Nrf2 pathway.