SOD1 Mouse Monoclonal Antibody
| Cat Number: | MAB-94790 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | 1H8 |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | IgG2a |
| Immunogen: | superoxide dismutase 1, soluble |
| Reactivity: | Human, Mouse, Rat |
| Molecular Weight: | 16-20 kDa |
| Purification: | Protein A+G purification |
| Synonyms: | Superoxide dismutase [Cu-Zn],Superoxide dismutase 1, hSod1 |
| Background: | Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage: | Store at -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
Various lysates were subjected to SDS PAGE followed by western blot with SOD1 antibody at dilution of 1:2000
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using SOD1 Antibody at dilution of 1:200